Anti-ACVR2A Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513886
CAPIPA5-13886EA 2801.79 CAD
CAPIPA5-13886
Anti-ACVR2A Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000

Type: Primary
Antigen: ACVR2A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Human
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