Anti-CLASP2 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA513992
CAPIPA5-13992EA 2444.36 CAD
CAPIPA5-13992
Anti-CLASP2 Rabbit Polyclonal Antibody
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000

Type: Primary
Antigen: CLASP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Human
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