Anti-SART1 Goat Polyclonal Antibody

Supplier: Pierce Biotechnology
CAPIPA5-18119EA 2943.07 CAD
Anti-SART1 Goat Polyclonal Antibody
This antibody is predicted to react with bovine, mouse and rat based on sequence homology. This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Recommended Dilutions: Western Blot: 0.03-0.1 ug/ml

Type: Primary
Antigen: SART1 (squamous cell carcinoma antigen recognized by T cells)
Clonality: polyclonal
Conjugation: unconjugated
Host: Goat
Isotype: none
Reactivity: Human
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