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CD54 [ICAM-1] non-lytic Recombinant Protein, Prosci

Supplier: Prosci
Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.

This recombinant proteins is for research use only.

Fusion-Tag: Fc Tag



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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 μg 90-397 75794-220 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/peptide name CD54 non-lytic
Protein synonyms Intercellular Adhesion Molecule 1, ICAM1
Protein/peptide type Recombinant
Species Mouse
Source CHO cells
Sequence 28-485
Purity >98% (SDS-PAGE)
Formulation Lyophilized from 0.2um-filtered solution in PBS.
Biological activity Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Storage Conditions Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
Protein type Recombinant
Modification Fc Tag
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