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CD134 [OX40] Recombinant Protein, Prosci

Supplier: Prosci
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4 + T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.

This recombinant proteins is for research use only.

Fusion-Tag: Fc Tag



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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 μg 90-407 75794-240 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/peptide name CD134
Protein synonyms TXGP1L, Tumor Necrosis Factor Receptor Superfamily Member 4, OX40, ACT35, TNFRSF4
Protein/peptide type Recombinant
Species Human
Source CHO cells
Sequence 29-216
Purity >98% (SDS-PAGE)
Formulation Lyophilized from 0.2um-filtered solution in PBS.
Biological activity Measured by its binding ability in a functional ELISA.
Storage Conditions Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
Protein type Recombinant
Modification Fc Tag
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