Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Pierce™Supplier: Thermo Scientific
Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt
, Sulfo NHS
, Hydroxy-2,5-dioxopyrrolidine-3-sulphonicacid sodium salt
Pierce™ Sulfo-NHS (N-hydroxysulfosuccinimide) is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.
- Improve efficiency of EDC coupling reactions
- Water-soluble and membrane-impermable
- Activate nanoparticles with amine-reactive Sulpho-NHS esters
- Crosslink proteins to carboxyl-coated beads or surfaces more efficiently
Sulfo-NHS (N-hydroxysulfosuccinimide) enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (—COOH) for conjugation with primary amines (—NH2). Derivatives are easily synthesized by mixing the Sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC (EDAC). The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.
Caution: For Research Use Only. Not for use in diagnostic procedures.
MW: 217.13 g/mol
CAS Number: 106627-54-7
Specification Test Results
|Labeling Method||Chemical Labeling|