Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Premium Grade, Pierce™Supplier: Thermo Scientific
Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid sodium salt
, Sulfo NHS
, Hydroxy-2,5-dioxopyrrolidine-3-sulphonicacid sodium salt
Thermo Scientific Pierce Premium Grade Sulfo-NHS is our highest quality formulation of this N-hydroxysuccinimide chemical modification reagent, specially characterized for applications where product integrity and risk minimization are paramount.
- Sulfo-NHS—use with EDC crosslinker to prepare amine-reactive NHS ester reagents
- High quality—identity and purity confirmed by several tests, including quantitative NMR
- Product integrity—enhanced level of testing and characterization compared to standard grade
- Lot retention—ample supply of past lots retained to ensure future process testing
- Change management—Change Control Notification (CCN) service
- Consistent manufacture—batch-specific manufacturing documentation review
Compared to the standard grade product, Premium Grade Sulfo-NHS provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. Sulfo-NHS (N-hydroxysulfosuccinimide) enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (—COOH) for conjugation with primary amines (—NH2). Derivatives are easily synthesized by mixing the sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC (EDAC). The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.
Caution: For Research Use Only. Not for use in diagnostic procedures.
MW: 217.13 g/mol
Storage Temperature: Refrigerator
CAS Number: 106627-54-7
Specification Test Results
|Labeling Method||Chemical Labeling|
|Quantity||500 mg /10 g|